Chapter 4 Helpful Hints/ Human Plasma Proteome

Chapter 4: Helpful Hints

This video is a song/rap about cells and their organelles. The video is set to the song "Empire State of Mind" by Jay Z, so the song goes to a popular tune that is easy to remember. There are lots of diagrams, pictures, and labels so one can identify the parts while hearing/singing about them. Lastly, the video shows both eukaryotic and prokaryotic cells, so one can identify the cell types and structures in both types.

So this video is about endosymbiosis. Endosymbiosis is how it is believed that mitochondria and chloroplasts ended up in cells. This video has clay figures clearly labeled to represent the large and small cells involved. It also has words describing what is happening during endosymbiosis. Last but certainly not least, it has "You've Got a Friend in Me" playing in the background which relates to the video and is also such a great song!

Human Plasma Proteome

This article talks about how the human plasma proteome holds a world of answers involving disease diagnosis and therapeutic monitoring. The plasma proteome is not the only proteome being studied, but it has the largest and deepest version of the human proteome. The plasma proteome not only included plasma proteins, but also included tissue proteins and multiple distinct immunoglobin sequences.

Before, standard proteomic technology only allowed for scientists to study 289 plasma proteins. However, new technologies are guaranteeing twice the amount of proteins to be studies in the near future. Research suggests that among these numerous plasma proteins are indicators of many human diseases. However, very few proteins are used in routine clinical diagnosis, and the rate of introduction of new protein test approved by the FDA has declined in the past ten years to one new protein per year.